AURKA —— 极光激酶A

AURKA

极光激酶A

aurora kinase A

该基因编码的蛋白质是细胞周期调节的激酶，在染色体分离过程中似乎参与了微管的形成和/或纺锤体极点的稳定。在相间细胞的中心体和有丝分裂的纺锤体极中发现了编码的蛋白质。该基因可能在肿瘤的发生和发展中起作用。在染色体1上发现了该基因的一个经过加工的假基因，在染色体10上也发现了一个未经加工的假基因。[由RefSeq提供，2008年7月]

The protein encoded by this gene is a cell cycle-regulated kinase that appears to be involved in microtubule formation and/or stabilization at the spindle pole during chromosome segregation. The encoded protein is found at the centrosome in interphase cells and at the spindle poles in mitosis. This gene may play a role in tumor development and progression. A processed pseudogene of this gene has been found on chromosome 1, and an unprocessed pseudogene has been found on chromosome 10. Multiple transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]