AURKB —— 极光激酶B

AURKB

极光激酶B

aurora kinase B

该基因编码丝氨酸/苏氨酸激酶的极光激酶亚家族的成员。编码该亚家族其他两个成员的基因位于19号和20号染色体上。这些激酶通过与微管的结合，参与有丝分裂和减数分裂过程中染色体排列和分离的调控。该基因的假基因位于8号染色体上。或者，已发现该基因的剪接转录变体。[由RefSeq提供，2015年9月]

This gene encodes a member of the aurora kinase subfamily of serine/threonine kinases. The genes encoding the other two members of this subfamily are located on chromosomes 19 and 20. These kinases participate in the regulation of alignment and segregation of chromosomes during mitosis and meiosis through association with microtubules. A pseudogene of this gene is located on chromosome 8. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2015]