医疗特长：对消化系统常见疾病（包括慢性胃炎、消化性溃疡、胃食管反流病）的诊断与治疗有丰富的临床经验；熟练掌握消化内镜技术。擅长胃食管反流病，消化性溃疡等酸相关性疾病以及肝胆疾病的诊治。研究方向：与肝胆肿瘤和癌前病变相关的基因调控和靶向治疗研究主要教育和工作经历：2010年获得卫生部重点学科专项基金资助，在美国德州大学西南医学中心从事2年博士后工作。主要领域是与肝胆肿瘤和癌前病变相关的基因调控和靶向治疗研究。近年来发表论著30余篇，分布在Hepatology，Am J Gastroenterol, Endoscopy等国际顶级学术期刊上。多项临床研究被国际胃食管反流病治疗指南引用，2013年被欧洲消化病年会颁发杰出学者奖项。所发表第一作者论文获美国生理学会评为年度最有价值研究并颁发证书。对消化系统常见疾病（包括慢性胃炎、消化性溃疡、胃食管反流病）的诊断与治疗有丰富的临床经验；熟练掌握消化内镜技术。擅长胃食管反流病，消化性溃疡等酸相关性疾病以及肝胆疾病的诊治。发表论著： （1）Lin Y, Zhai E, Liao B, Xu L, Zhang X, Peng S, He Y, Cai S, Zeng Z, Chen M.Autocrine VEGF signaling promotes cell proliferation through a PLC-dependent pathway and modulates Apatinib treatment efficacy in gastric cancer. Oncotarget. 2017 Feb 14;8(7):11990-12002. doi: 10.18632/oncotarget.14467. PubMed PMID:28061477; PubMed Central PMCID: PMC5355320. （2）彭穗，王晶，彭振维，许丽霞，郭宇，匡铭，携带缺氧诱导因子-1a siRNA的叶酸靶向化的磁性纳米复合物抑制肝癌干细胞增殖的实验研究，中华细胞与干细胞杂志，2016.07.06，6（1）：42~46 （3）Peng H, Zhang Q, Li J, Zhang N, Hua Y, Xu L, Deng Y, Lai J, Peng Z, Peng B,Chen M, Peng S, Kuang M. Apatinib inhibits VEGF signaling and promotes apoptosis in intrahepatic cholangiocarcinoma. Oncotarget. 2016 Mar 29;7(13):17220-9. doi:10.18632/oncotarget.7948. PubMed PMID: 26967384; PubMed Central PMCID:PMC4941382. （4）Peng S, Zhang Y, Peng H, Ke Z, Xu L, Su T, Tsung A, Tohme S, Huang H, Zhang Q,Lencioni R, Zeng Z, Peng B, Chen M, Kuang M. Intracellular autocrine VEGF signaling promotes EBDC cell proliferation, which can be inhibited by Apatinib.Cancer Lett. 2016 Apr 10;373(2):193-202. doi: 10.1016/j.canlet.2016.01.015. Epub 2016 Jan 19. PubMed PMID: 26805764. （5）Xiao Y, Liang M, Peng S, Zhang N, Chen M. Tailored therapy for the refractoryGERD patients by combined multichannel intraluminal impedance-pH monitoring. JGastroenterol Hepatol. 2016 Feb;31(2):350-4. doi: 10.1111/jgh.13049. PubMed PMID:26202002. （6）Peng S, Huo X, Rezaei D, Zhang Q, Zhang X, Yu C, Asanuma K, Cheng E, Pham TH,Wang DH, Chen M, Souza RF, Spechler SJ. In Barrett\'s esophagus patients andBarrett\'s cell lines, ursodeoxycholic acid increases antioxidant expression andprevents DNA damage by bile acids. Am J Physiol Gastrointest Liver Physiol. 2014Jul 15;307(2):G129-39. doi: 10.1152/ajpgi.00085.2014. Epub 2014 May 22. PubMedPMID: 24852569; PubMed Central PMCID: PMC4101678. （7）彭穗， 刘芙蓉，何铭辉，许丽霞，彭振维，郭宇，匡铭，靶向多功能纳米造影剂对肝癌细胞MRI显像和基因传输的研究，功能与分子医学影像学，2015，10，01，4（4）：790~793 （8）Peng S, Wang Y, Peng H, Chen D, Shen S, Peng B, Chen M, Lencioni R, Kuang M.Autocrine vascular endothelial growth factor signaling promotes cellproliferation and modulates sorafenib treatment efficacy in hepatocellularcarcinoma. Hepatology. 2014 Oct;60(4):1264-77. doi: 10.1002/hep.27236. Epub 2014Aug 25. PubMed PMID: 24849467. （9）Zhang Q, Yu C, Peng S, Xu H, Wright E, Zhang X, Huo X, Cheng E, Pham TH,Asanuma K, Hatanpaa KJ, Rezai D, Wang DH, Sarode V, Melton S, Genta RM, SpechlerSJ, Souza RF. Autocrine VEGF signaling promotes proliferation of neoplasticBarrett\'s epithelial cells through a PLC-dependent pathway. Gastroenterology.2014 Feb;146(2):461-72.e6. doi: 10.1053/j.gastro.2013.10.011. Epub 2013 Oct 9.PubMed PMID: 24120473; PubMed Central PMCID: PMC3899829. （10）Li J, Xiao Y, Peng S, Lin J, Chen M. Characteristics of belching, swallowing,and gastroesophageal reflux in belching patients based on Rome III criteria. JGastroenterol Hepatol. 2013 Aug;28(8):1282-7. doi: 10.1111/jgh.12187. PubMedPMID: 23488810. （11）Peng S, Xiao YL, Cui Y, Lin JK, Zhang N, Hu PJ, Chen MH. High-doseesomeprazole is required for intraesophageal acid control in gastroesophagealreflux disease patients with hiatus hernia. J Gastroenterol Hepatol. 2012May;27(5):893-8. doi: 10.1111/j.1440-1746.2011.06969.x. PubMed PMID: 22098387. （12）Xiong LS, Peng S, Peng XZ, Chen W, Hu PJ, Chen MH. [A population-basedepidemiologic study of bowel habits in Guangdong province]. Zhonghua Liu XingBing Xue Za Zhi. 2010 Jun;31(6):662-5. Chinese. PubMed PMID: 21163099. （13）Xiao YL, Peng S, Tao J, Wang AJ, Lin JK, Hu PJ, Chen MH. Prevalence andsymptom pattern of pathologic esophageal acid reflux in patients with functionaldyspepsia based on the Rome III criteria. Am J Gastroenterol. 2010Dec;105(12):2626-31. doi: 10.1038/ajg.2010.351. Epub 2010 Sep 7. PubMed PMID:20823838. （14）Peng S, Xiong LS, Xiao YL, Wang AJ, Lin JK, Hu PJ, Chen MH. Relationshipbetween symptom response and esophageal pH level on standard dose of esomeprazoletreatment for gastroesophageal reflux disease. Chin Med J (Engl). 2010 Aug5;123(15):2012-7. PubMed PMID: 20819534. （15）Peng S, Xiong LS, Xiao YL, Lin JK, Wang AJ, Zhang N, Hu PJ, Chen MH. Promptupper endoscopy is an appropriate initial management in uninvestigated chinesepatients with typical reflux symptoms. Am J Gastroenterol. 2010Sep;105(9):1947-52. doi: 10.1038/ajg.2010.121. Epub 2010 Mar 30. PubMed PMID:20354508. （16）Xiao YL, Lin JK, Cheung TK, Wong NY, Hung IF, Wong BC, Peng S, Wang AJ, ChenMH. Reflux profile of Chinese gastroesophageal reflux disease patients withcombined multichannel intraluminal impedance-pH monitoring. J GastroenterolHepatol. 2009 Jun;24(6):1113-8. doi: 10.1111/j.1440-1746.2009.05861.x. PubMedPMID: 19638089. （17）Wang A, Liao X, Xiong L, Peng S, Xiao Y, Liu S, Hu P, Chen M. The clinicaloverlap between functional dyspepsia and irritable bowel syndrome based on RomeIII criteria. BMC Gastroenterol. 2008 Sep 23;8:43. doi: 10.1186/1471-230X-8-43.PubMed PMID: 18808723; PubMed Central PMCID: PMC2569040. （18）Tao J, Xiao YL, Chen MH, Peng S, Lin JK, Xiong LS, Hu PJ. [Changes ofintercellular spaces of esophageal epithelium in patients with gastroesophagealreflux disease before and after esomeprazole treatment]. Zhonghua Yi Xue Za Zhi.2007 Feb 6;87(6):392-5. Chinese. PubMed PMID: 17456380. （19）Gao X, Hu PJ, He Y, Liao SY, Peng S, Chen MH. [Diagnostic role ofanti-saccharomyces cerevisiae and antineutrophil cytoplasmic autoantibodies ininflammatory bowel disease]. Zhonghua Nei Ke Za Zhi. 2005 Jun;44(6):428-30.Chinese. PubMed PMID: 16008854.其他主要工作成绩：作为课题负责人主持包括国家自然科学基金在内的多项科研基金；发表学术论文30余篇，分布在Hepatology，Am J Gastroenterol, Endoscopy等国际顶级学术期刊上。多项临床研究被国际胃食管反流病治疗指南引用，2013年被欧洲消化病年会颁发杰出学者奖项。所发表第一作者论文获美国生理学会评为年度最有价值研究并颁发证书。