沈亚星   副主任医师，医学博士，北京协和医学院博士后 美国心胸外科协会（American Association for Thoracic Surgery，AATS）Evarts A. Graham Fellow 美国胸外科医师协会（Society of Thoracic Surgeons, STS）国际会员 欧洲胸外科医师协会（European Society of Thoracic Surgeons, ESTS）委员 欧洲心胸外科协会（European Association for Cardio-Thoracic Surgery, EACTS）委员 世界肺癌协会（International Association for the Study of Lung Cancer, IASLC）委员 AME出版社副社长 《胸部疾病杂志》（Journal of Thoracic Disease）学术沙龙委员 　　沈亚星为复旦大学外科学博士、北京协和医学院博士后，师从中国医学科学院肿瘤医院赫捷院士，美国心胸外科学会Evarts A. Graham学者。参加胸外科工作以来，以第一作者完成胸外科三大顶尖杂志Journal of Thoracic and Cardiovascular Surgery（JTCVS）、Annals of Thoracic Surgery（ATS）及European Journal of Cardio-thoracic Surgery（EJCTS）论文发表大满贯，先后完成世界顶尖四大胸外科学术会议：美国心胸外科协会（AATS）、欧洲胸外科医师协会（ESTS）、美国胸外科医师协会（STS）、欧洲心胸外科协会 （EACTS）大会发言大满贯。主持国家青年自然科学基金1项（《经颈单孔微创食管癌切除术的外科解剖学研究》批准号：81400681），中国博士后科学基金面上项目1项（批准号：2018M631394）。提出“经颈内镜-腔镜联合微创食管癌切除术”的手术创新并发表于外科学顶尖期刊《外科学年鉴》（Annals of Surgery）, 获得全球心胸外科青年医师最高奖项Evarts A. Graham学者奖（2015年）。2018年复旦大学十佳医务工作者、2019年复旦大学十佳医务青年获得者，2020年复旦大学附属中山医院援鄂医疗队成员, 2021年复旦大学五四青年奖章提名。参与国家自然科学基金（2014年）、上海市科委（2012年）及上海市卫生局研究（2012年）项目各1项。2016年获得上海市科技进步二等奖（第三完成人）。 相关学术成果 论文 Shen Y,Zhang Y, He M, et al. Advancing Gastroscope From Intraluminal to Extraluminal Dissection: Primary Experience of Laparo-gastroscopic Esophagectomy. Ann Surg. 2022 Apr 1; 275(4): e659- e663.  Shen Y,Zhang H, Yao S, et al. Methionine oxidation of CLK4 promotes the metabolic switch and redox homeostasis in esophageal carcinoma via inhibiting MITF selective autophagy. Clin Transl Med. 2022 Jan;12(1): e719.  Shen Y, Chen X, Hou J, Chen Y, Fang Y, Xue Z, D'Journo XB, Cerfolio RJ, Fernando HC, Fiorelli A, Brunelli A, Cang J, Tan L, Wang H. The effect of enhanced recovery after minimally invasive esophagectomy: a randomized controlled trial. Surg Endosc. 2022 Jun 30. doi: 10.1007/s00464-022-09385-6. Online ahead of print. Ma GG, Shen YX, Wu L, Luo Z, Zhu CW, Chen SY, Yu KH, Li F. Effect of liver injury on prognosis and treatment of hospitalized patients with COVID-19 pneumonia. Ann Transl Med. 2021 Jan;9(1):10. （共同第一作者） Chen X, Xue S, Xu J, Zhong M, Liu X, Lin G, Shen Y, Tan L. Transcervical minimally invasive esophagectomy: hemodynamic study on an animal model. J Thorac Dis. 2020 Nov;12(11):6505-6513. （通讯作者） Shen Y,Song J, Wang Y, Chen Z, Zhang L, Yu J, Zhu D, Zhong M. M2 macrophages promote pulmonary endothelial cells regeneration in sepsis-induced acute lung injury. Ann Transl Med. 2019 Apr; 7(7): 142. Wang Y, Shen Y, Sun X, Hong TL, Huang LS, Zhong M. Prognostic roles of the expression of sphingosine-1-phosphate metabolism enzymes in non-small cell lung cancer. Transl Lung Cancer Res. 2019 Oct;8(5):674-681. Lei R, Liu Q, Wang Y, Wang H, Shen Y. Analysis of major programs in the field of health science funded by the National Natural Science Foundation of China between the years 2010 and 2018. Ann Transl Med. 2019 Jun;7(12):268. Shen Y, Zhang Y, Sun J, Gu J, Yuan Y, Wang Q. Transaxillary uniportal video assisted thoracoscopic surgery for right upper lobectomy. J Thorac Dis. 2018; 10: E214-E217. Hao W, Shen Y, Feng M, Wang H, Lin M, Fang Y, Tan L. Aspirin acts in esophageal cancer: a brief review. J Thorac Dis. 2018 Apr;10(4):2490-2497. （通讯作者） Lin M, Shen Y, Wang H, Fang Y, Qian C, Xu S, Ge D, Feng M, Tan L, Wang Q. A comparison between two lung ventilation with CO2 artificial pneumothorax and one lung ventilation during thoracic phase of minimally invasive esophagectomy. J Thorac Dis. 2018 Mar;10(3):1912-1918.  Shen W, Shen Y, Tan L, Jin C, Xi Y. A nomogram for predicting lymph node metastasis in surgically resected T1 esophageal squamous cell carcinoma. J Thorac Dis. 2018 Jul;10(7):4178-4185. Liang W, He J, Shen Y, Shen J, He Q, Zhang J, Jiang G, Wang Q, Liu L, Gao S, Liu D, Wang Z, Zhu Z, Ng CS, Liu CC, Horsleben Petersen R, Rocco G, D'Amico T, Brunelli A, Chen H, Zhi X, Liu B, Yang Y, Chen W, Zhou Q, He J. Impact of Examined Lymph Node Count on Precise Staging and Long-Term Survival of Resected Non-Small-Cell Lung Cancer: A Population Study of the US SEER Database and a Chinese Multi-Institutional Registry. J Clin Oncol. 2017 Apr 10;35(11):1162-1170. （共同第一作者） Shen Y,Wang H, Feng M, Xi Y, Tan L, Wang Q. Single- versus multiple-port thoracoscopic lobectomy for lung cancer: a propensity-matched study. Eur J Cardiothorac Surg. 2016; 49 Suppl 1: i48-53. [ESI热点论文] Shen Y,Feng M, Tan L, Wang H, Li J, Xi Y, Tan L, Wang Q. Thoracoscopic esophagectomy in prone versus decubitus position: Ergonomic evaluation from a randomized and controlled study. Ann Thorac Surg. 2014, 9: 1072-1078. Shen Y,Wang H, Feng M, Tan L, Wang Q. The effect of narrowed gastric conduits on anastomotic leakage following minimally invasive esophagectomy. Interact Cardiovasc Thorac Surg. 2014, 19: 263-268. Shen Y, Feng M, Khan MA, Wang H, Tan L, Wang Q. A simple method minimizes chylothorax following minimally invasive esophagectomy. J Am Coll Surg. 2014, 218: 108-112. Shen Y, Zhong M, Wu W, Wang H, Tan L, Wang Q. The impact of tidal volume on pulmonary complications following minimally invasive esophagectomy: A randomized and controlled study. J Thorac Cardiovasc Surg. 2013,146: 1267-1274. Shen Y, Zhong M, Jiang W, Fan H, Wang H, Wang Q. Video-assisted radiofrequency ablation for pleural disseminated non-small cell lung cancer. BMC Surg. 2013, 13; 13(1): 19. Shen Y, Zhang Y,Tan L, Feng M, Wang H, Khan MA, Liang M, Wang Q. Extensive mediastinal lymphadenectomy during minimally invasive esophagectomy: Optimal results from a single center. J Gastrointest Surg. 2012, 16: 715-721. Shen Y,Zhong M, Tan L. Fondaparinux versus low molecular weight heparin following esophagectomy: results from a randomized and controlled trial. Chest. 2014, 145 (3Suppl): 535D. doi: 10.1378/ chest. 1921851. Wang H, Shen Y, Feng M, Zhang Y, Jiang W, Xu S, Tan L, Wang Q. Outcomes, quality of life, and survival after esophagectomy for squamous cell carcinoma: A propensity score-matched comparison of operative approaches. J Thorac Cardiovasc Surg. 2015，149: 1006-1015.（共同第一作者） Li J, Shen Y, Tan L, Feng M, Wang H, Xi Y, Wang Q. Is minimally invasive esophagectomy beneficial to elderly patients with esophageal cancer? Surg Endosc. 2015，29: 925-930. （共同第一作者） Li S, Liu X, Shen Y, Wang H, Feng M, Tan L. Laparoscopic repair of Morgagni hernia by artificial pericardium patch in an adult obese patient. J Thorac Dis. 2015，7: 754-757. （通讯作者） Feng M, Shen Y, Wang H, Tan L, Zhang Y, Khan MA, Wang Q. Thoracolaparoscopic esophagectomy: Is the prone position a safe alternative to the decubitus position? J Am Coll Surg. 2012, 214:838-844. Yuan Y, Shen Y, Xue L, Fan H. miR-140 Suppresses Tumor Growth and Metastasis of Non-Small Cell Lung Cancer by Targeting Insulin-Like Growth Factor 1 Receptor. PLoS One. 2013，8: e73604. Liang M, Wang H, Tan L, Feng M, Shen Y, Wang Q. Successful treatment of thyrotoxic crisis after esophagectomy in an elderly woman with hyperthyroidism.Ann Thorac Surg. 2012, 93: e141-142. Jiang W, Pang XG, Wang Q, Shen YX, Chen XK, XiJJ. Prognostic role of Twist, Slug, and Foxc2 expression in stage I non-small-cell lung cancer after curative resection. Clin Lung Cancer.2012，13: 280-287. Li J, Chen X, Shen Y, Hou Y, Zhang S, Wang H, Feng M, Tan L, Wang Q, Zeng Z. A rare collision tumor of squamous carcinoma and small cell carcinoma in esophagus involved with separate lymph nodes: a case report. J Thorac Dis. 2013，5: E203-206. 课题 中国博士后科学基金面上项目“Aspirin及NOSH-Aspirin抗食管癌机制研究” 批准号2018M631394 国家青年自然科学基金课题“经颈单孔微创食管切除术的外科解剖学研究”项目批准号主持人81400681 2015年1月-2017年12月 国家自然科学基金课题“基于灰色神经理论的人工气胸新技术在微创食管手术中应用的安全性分析”项目批准号81370587 主要研究人员（第四参与人）2014年7月-2017年12月 上海市科委课题  “新型经颈单孔内窥镜食管手术的实验研究” 12ZR1405400课题主要研究人员（第四参与人）2012年7月-2015年6月 上海市卫生局课题  “shRNA介导的Caspase 3基因沉默对移植肺缺血再灌注损伤保护作用的研究” 课题20114252主要研究人员（第三参与人）2012年1月-2014年9月 大会发言 Shen Y, Tan L. Comparison of Pulmonary function changes between Neoadjuvant Chemo and Chemoradiation for Minimally Invasive Esophagectomy: A Randomized and controlled Trial. 32th European Association for Cardiothoracic Surgery (EACTS) Annual Meeting, Milan, Italy, October 18-20, 2018. Shen Y, Tan L. Learning Curve for Uniportal VATS Lobectomy Results from 120 Consecutive Patients. 34th Annual Meeting of the Japanese Association for Chest Surgery (JACS), Fukuoka, Japan, May 18-19, 2017. Shen Y, Tan L. Minimally Invasive Esophagectomy: How Robotic Does in Decubitus Position? The 2nd Asian Congress of Robotic Surgery (ACRS 2016), Gyeongju, Korea, November 25-26, 2016. Shen Y, Tan L. Extensive Mediastinal Lymphadenectomy during Thoracoscopic Esophagectomy for Esophageal Cancer. The 2nd Asian Congress of Robotic Surgery (ACRS 2016), Gyeongju, Korea, November 25-26, 2016. Shen Y, Tan L, D’Amico T.Trans-Cervical MIE under Artificial Pneumo-Mediastinum. American Association for Thoracic Surgery, AATS focus on Thoracic Surgery，October, 2015. Boston, MA, US, 2015.     Shen Y, Zhong M, Tan L. Fondaparinux versus Low Molecular Weight Heparin following Esophagectomy: Results from a Randomized and Controlled Trial. CHEST World Congress 2014 American College of Chest Physicians, ACCP March 21-24. Madrid, Spain, 2014. Shen Y, Wang H, Feng M, Tan L, Li J，Wang Q. Thoracoscopic esophagectomy in prone versus decubitus position: Ergonomic evaluation from a randomized and controlled study. 50th Annual meeting, Society of Thoracic Surgeons, STS, P242 January 25-29. Orlando, FL, US, 2014. Shen Y, Zhong M, Wu W, Tan L，Feng M, Wang H, Wang Q. The effect of tidal volume on pulmonary complications following minimally invasive esophagcetomy: A randomized and controlled trial. 93rd Annual meeting, American Association for Thoracic Surgery, AATS，P154 May 4-8, 2013. Minneapolis, MN, US, 2013.        Shen Y, Wang H, Feng M, Tan L, Wang Q，Li J. The effect of narrow gastric conduit on anastomotic leakage following minimally invasive esophagectomy. 21st European Conference on General Thoracic Surgery, ESTS,F-088. P123 May 26-29, 2013. Birmingham, UK. Shen Y, Feng M, Wang H, Tan L, Wang Q，Li J. Extensive mediastinal lymphadenectomy during minimally invasive esophagectomy: Oncological outcomes from single center. 21st European Conference on General Thoracic Surgery, ESTS,F-058. P85 May 26-29, 2013. Birmingham, UK. Shen Y, Tan L. A simple and safe method minimizes chylothorax following minimally invasive esophagectomy. World Congress of the International Society for Diseases of the Esophagus，ISDE, P116A. October 15-17, 2012. Venice, Italy, 2012.