一级主任医师/博导。科室及职务：肿瘤中心主任兼肿瘤学教研室主任、学科带头人。诊疗专长：1、肺癌的多学科精准诊疗2、各种实体肿瘤的精准诊疗。学术任职与荣誉：国家第五届“国之名医”——卓越建树专家；国家自然基金和科技奖评审专家；国家教育部学位评审专家；中国科协科技人才奖项评审专家；国家卫健委医政医管局《肺癌诊疗指南》专家组成员；国家癌症中心肺癌质控专家；国家抗肿瘤药物临床应用监测委员会委员国家新型抗肿瘤药物合理应用专家委员会委员；中华医学会继续医学教育教材《肺癌》分册副主编、人民卫生出版社《肿瘤学》教材编委；中华放射肿瘤学杂志编委；中华肿瘤防治杂志编委；肿瘤学杂志副主编；国际肿瘤学杂志编委；武汉大学学报医学版编委；中国医师协会肿瘤多学科诊疗专业委员会副主任委员兼总干事；世界华人肿瘤医师协会常委兼胸部肿瘤分会副主任委员；中国医促会胸部肿瘤分会副主任委员；吴阶平医学基金会肿瘤多学科诊疗专委会副主任委员；中国临床肿瘤学会（CSCO）常务理事；CSCO老年肿瘤专委会副主委，肺癌、大数据专委会常委；中国抗癌协会肺癌、科普、肿瘤多学科诊疗专委会常委；湖北省“323”肺癌质控专家委员会主任委员；湖北省临床肿瘤学会（ESCO）理事长兼肺癌专委员会主任委员；武汉医学会放射肿瘤治疗学分会主任委员。科研成果：部分科研论文：[1]Chen,L.,Q.Zhou,P.Zhang,etal.,DirectstimulationofdenovonucleotidesynthesisbyO-GlcNAcylation[J].NatChemBiol,2023.DOI:10.1038/s41589-023-01354-x.[2]Li,Y.,J.Chen,B.Wang,etal.,FOXK2affectscancercellresponsetochemotherapybypromotingnucleotidedenovosynthesis[J].DrugResistUpdat,2023.67:p.100926.DOI:10.1016/j.drup.2023.100926.[3]Cheng,Y.,Z.Gao,T.Zhang,etal.,Decodingm(6)ARNAmethylomeidentifiesPRMT6-regulatedlipidtransportpromotingAMLstemcellmaintenance[J].CellStemCell,2023.30(1):p.69-85.e7.DOI:10.1016/j.stem.2022.12.003.[4]Chu,Y.,Y.Yao,Q.Hu,etal.,RiskscoreModelBasedonOxidativeStress-RelatedGenesMayFacilitatethePrognosisEvaluationforPatientsWithColonCancer[J].ClinTranslGastroenterol,2023.14(6):p.e00582.DOI:10.14309/ctg.0000000000000582.[5]Ran,Z.,L.Zhang,M.Dong,etal.,O-GlcNAcylation:ACrucialRegulatorinCancer-AssociatedBiologicalEvents[J].CellBiochemBiophys,2023.DOI:10.1007/s12013-023-01146-z.[6]Zhao,C.,T.Xu,Y.Yao,etal.,Comparisonofcase-basedlearningusingWatsonforoncologyandtraditionalmethodinteachingundergraduatemedicalstudents[J].IntJMedInform,2023.177:p.105117.DOI:10.1016/j.ijmedinf.2023.105117.[7]Chen,L.,Y.Weng,X.Cui,etal.,ComprehensiveanalysesofaCD8(+)Tcellinfiltrationrelatedgenesignaturewithregardtothepredictionofprognosisandimmunotherapyresponseinlungsquamouscellcarcinoma[J].BMCBioinformatics,2023.24(1):p.238.DOI:10.1186/s12859-023-05302-3.[8]Liu,Z.,J.Wang,F.Liao,etal.,Tumor-EducatedPlateletsFacilitateThrombusFormationThroughMigration[J].FrontOncol,2022.12:p.857865.DOI:10.3389/fonc.2022.857865.[9]Fu,X.,W.Tan,Q.Song,etal.,BRCA1andBreastCancer:MolecularMechanismsandTherapeuticStrategies[J].FrontCellDevBiol,2022.10:p.813457.DOI:10.3389/fcell.2022.813457.[10]Ren,X.,W.Wen,X.Fan,etal.,COVID-19immunefeaturesrevealedbyalarge-scalesingle-celltranscriptomeatlas[J].Cell,2021.184(23):p.5838.DOI:10.1016/j.cell.2021.10.023.[11]Zheng,S.,Q.Song,P.Zhang,MetabolicModifications,Inflammation,andCancerImmunotherapy[J].FrontOncol,2021.11:p.703681.DOI:10.3389/fonc.2021.703681.[12]Yu,L.,H.Gong,Q.Li,etal.,SurvivalAnalysisofRadiationTherapyinOvarianCancer:ASEERDatabaseAnalysis[J].JOncol,2021.2021:p.8849039.DOI:10.1155/2021/8849039.[13]Yu,D.,W.Hu,L.Chen,etal.,EffectofradiotherapyinterruptionduetoCOVID-19outbreak[J].RadiotherOncol,2021.155:p.1-2.DOI:10.1016/j.radonc.2020.09.055.[14]Yang,S.,Y.Yao,Y.Dong,etal.,PredictionofRadiationPneumonitisUsingGenome-ScaleFluxAnalysisofRNA-SeqDerivedFromPeripheralBlood[J].FrontMed(Lausanne),2021.8:p.715961.DOI:10.3389/fmed.2021.715961.[15]Tan,W.,P.Jiang,W.Zhang,etal.,Posttranscriptionalregulationofdenovolipogenesisbyglucose-inducedO-GlcNAcylation[J].MolCell,2021.81(9):p.1890-1904.e7.DOI:10.1016/j.molcel.2021.02.009.[16]Liu,C.,K.Song,Q.Hu,etal.,HavinggastroesophagealcancerisassociatedwithincreasedriskofsevereCOVID-19-relatedeventsinpatientswithdigestivetractcancer:Amulticenter,retrospective,cohortstudy[J].IntJCancer,2021.148(7):p.1789-1793.DOI:10.1002/ijc.33452.[17]Lei,T.,J.Li,H.Zhong,etal.,PostoperativeRadiotherapyforPatientsWithResectableStageIII-N2Non-SmallCellLungCancer:ASystematicReviewandMeta-Analysis[J].FrontOncol,2021.11:p.680615.DOI:10.3389/fonc.2021.680615.[18]He,H.,T.Xu,P.Li,etal.,Anti-PD-1ImmunotherapyCombinedWithStereotacticBodyRadiationTherapyandGM-CSFasSalvageTherapyinaPD-L1-PositivePatientWithRefractoryMetastaticThyroidHürthleCellCarcinoma:ACaseReportandLiteratureReview[J].FrontOncol,2021.11:p.782646.DOI:10.3389/fonc.2021.782646.[19]Zuo,H.,L.Chen,N.Li,etal.,IdentificationofaUbiquitination-RelatedGeneRiskModelforPredictingSurvivalinPatientsWithPancreaticCancer[J].FrontGenet,2020.11:p.612196.DOI:10.3389/fgene.2020.612196.[20]Wu,J.,H.Zhang,L.Li,etal.,Anomogramforpredictingoverallsurvivalinpatientswithlow-gradeendometrialstromalsarcoma:Apopulation-basedanalysis[J].CancerCommun(Lond),2020.40(7):p.301-312.DOI:10.1002/cac2.12067.[21]Liu,C.,L.Li,K.Song,etal.,AnomogramforpredictingmortalityinpatientswithCOVID-19andsolidtumors:amulticenterretrospectivecohortstudy[J].JImmunotherCancer,2020.8(2).DOI:10.1136/jitc-2020-001314.[22]Hu,Z.,S.Mi,T.Zhao,etal.,BGL3lncRNAmediatesretentionoftheBRCA1/BARD1complexatDNAdamagesites[J].Emboj,2020.39(12):p.e104133.DOI:10.15252/embj.2019104133.[23]Gong,H.,H.Feng,L.Yu,etal.,CoronavirusDisease2019InfectionAmongMedicalStaffinWuhan:ARetrospectiveStudyFromaSingleCenter[J].Chest,2020.158(4):p.1409-1412.DOI:10.1016/j.chest.2020.05.529.[24]Peng,Y.,Q.Liao,W.Tan,etal.,ThedeubiquitylatingenzymeUSP15regulateshomologousrecombinationrepairandcancercellresponsetoPARPinhibitors[J].NatCommun,2019.10(1):p.1224.DOI:10.1038/s41467-019-09232-8.[25]Yao,Y.,Z.Zheng,Q.Song,Mesenchymalstemcells:Adouble-edgedswordinradiation-inducedlunginjury[J].ThoracCancer,2018.9(2):p.208-217.DOI:10.1111/1759-7714.12573.部分科研项目及成果：1、国家自然科学基金，AIM2炎症小体在放射性肺炎发生中的调控机制，81372407,主持2、国家自然科学基金，TMCC2在骨髓增殖性肿瘤中的功能和机制研究，81670123，主持3、国家自然科学基金，精氨酸甲基化修饰抑制NADP合成的分子机制及生物学功能研究，82273094，主持4、获湖北省科技进步二等奖，第一完成人5、《肺癌诊疗指南》，中华医学会，专家组成员6、《临床肿瘤规范化诊疗实践与进展--肺癌分册》，人民卫生出版社，副主编7、《肿瘤精准放射治疗学临床要点》，湖北科学技术出版社，主编8、《肿瘤精准放疗靶区勾画图谱》，湖北科学技术出版社，主编9、《精准肿瘤学解析—进展及案例》科学出版社，副主译