薛志宏专家、博士生导师
四川大学华西第二医院西部妇幼医学研究院
1.职称:研究员,2.学历:博士,3.研究方向:调控心脏发育的新作用因子及其分子作用机制;生心祖细胞的新亚群及其分子标记的分离;心脏谱系细胞体外定向分化方法的探索与优化。4.邮件:xuez@scu.edu.cn,5.个人经历:2014.3—2017.7.1博士后,美国麻省理工学院,2014.3—2017.8 2009.1—2014.2博士,美国德克萨斯西南医学中心—达拉斯分校,6.代表性论文:(1)Xue,Z.,Ye,Q.,Anson,S.R.,Yang,J.,Xiao,G.,Kowbel,D.,Glass,N.L.,Crosthwaite,S.K.,and Liu,Y. (2014). Transcriptional interference by antisense RNA is required for circadian clock function. Nature 514,650-653. (IF=38.1),(2)Xue,Z.,Hennelly,S.,Doyle,B.,Gulati,A.A.,Novikova,I.V.,Sanbonmatsu,K.Y.,and Boyer,L.A. (2016). A G-Rich Motif in the lncRNA Braveheart Interacts with a Zinc-Finger Transcription Factor to Specify the Cardiovascular Lineage. Mol Cell 64,37-50. (Highlighted by Mol Cell,Nature Chemical Biology,and Science Signaling) (IF=14.0),(3)Xue,Z.,Yuan,H.,Guo,J.,and Liu,Y. (2012). Reconstitution of an Argonaute-dependent small RNA biogenesis pathway reveals a handover mechanism involving the RNA exosome and the exonuclease QIP. Mol Cell 46,299-310. (IF=14.0),(4)Lee,H.C.*,Li,L.*,Gu,W.*,Xue,Z.,Crosthwaite,S.K.,Pertsemlidis,A.,Lewis,Z.A.,Freitag,M.,Selker,E.U.,Mello,C.C.,Liu,Y. (2010). Diverse pathways generate microRNA-like RNAs and Dicer-independent small interfering RNAs in fungi. Mol Cell 38,803-814. (IF=14.0),(5)Zhang,Z.*,Chang,S.S.*,Zhang,Z.,Xue,Z.,Zhang,H.,Li,S.,and Liu,Y. (2013). Homologous recombination as a mechanism to recognize repetitive DNA sequences in an RNAi pathway. Genes Dev 27,145-150. (IF=10.0),(6)Yang,Q.,Li,L.,Xue,Z.,Ye,Q.,Zhang,L.,Li,S.,and Liu,Y. (2013). Transcription of the major Neurospora crassa microRNA-like small RNAs relies on RNA polymerase III. PLoS Genet 9,e1003227. (IF=6.7),(7)Dang,Y.,Li,L.,Guo,W.,Xue,Z.,and Liu,Y. (2013). Convergent transcription induces dynamic DNA methylation at disiRNA loci. PLoS Genet 9,e1003761. (IF=6.7),(8)Dang,Y.,Yang,Q.,Xue,Z.,and Liu,Y. (2011). RNA interference in fungi: pathways,functions,and applications. Eukaryot Cell 10,1148-1155. (IF=3.4)