鲍燕研究员
中山大学孙逸仙纪念医院基础与转化医学研究中心
研究员,博士生导师。中山大学百人计划引进人才。主要研究方向是开发精准靶向裂解细胞膜的抗肿瘤及抗菌药物。在Nature Nanotechnology、Science Advances、PNAS等期刊发表论文。主持国家自然科学基金-青年科学基金项目和面上项目、广东省自然科学基金-杰出青年项目等。Mingdong Liu#,Liangqi Huang#,Weinan Zhang#,Xiaochuan Wang,Yuanyuan Geng,Yuhao Zhang,Li Wang,Wenbin Zhang,Yun-Jiao Zhang,Shiyan Xiao*,Yan Bao*,Menghua Xiong*,and Jun Wang*,A transistor-like pH-sensitive nanodetergent for selective cancer therapy,Nature Nanotechnology,2022 May;17(5):541-551.(影响因子34.9,中科院SCI期刊大类分区:材料科学1区)ISSN: 1748-3387,Yangbin Liang#,Yuhao Zhang#,Yu Huang#,Cheng Xu#,Jingxian Chen,Xinshuang Zhang,Bingchuan Huang,Zhanhui Gan,Xuehui Dong,Songyin Huang,Chengrun Li,Shuyi Jia,Pengfei Zhang,Yueling Yuan,Houbing Zhang,Yucai Wang,Bing Yuan,Yan Bao*,Shiyan Xiao*,Menghua Xiong*,Helicity-directed recognition of bacterial phospholipid via radially amphiphilic antimicrobial peptides,Science Advances,2024 Aug 30;10(35):eadn9435. (影响因子12.5,中科院SCI期刊大类分区:综合性期刊1区)ISSN: 2375-2548,Xinshuang Zhang #,Dong Luo #,Jie Hu #,Kangxiu Wu,Shuyi Jia,Xueyi Li,Songyin Huang,Houbing Zhang,Dokyun Kim,Yuzhi Hong,Liping Zhao,Menghua Xiong*,and Yan Bao*,Selective Recognition of Bacterial Phospholipids by Antimicrobial Peptides: Employing a Host-Guest-Mediated Competitive Inhibition Strategy. Biomaterials. 2025 May 6:322:123392(影响因子12.9,中科院SCI期刊大类分区:医学1区)ISSN: 0142-9612,Xinshuang Zhang#,Shuyi Jia#,Xueyi Li#,Liping Zhao,Kangxiu Wu,Songyin Huang,Fan Zhang,Houbing Zhang,Dong Luo*,Menghua Xiong*,and Yan Bao*,Hydrophobicity-to-cationic amphipathicity transformable antimicrobial polypeptides for the prevention of medical implant-associated infections. Biomaterials. 2025 Jul 21:325:123564.(影响因子12.9,中科院SCI期刊大类分区:医学1区) ISSN: 0142-9612,Yang Bo,Yunjiang Jiang,Kangmei Chen,Kaimin Cai,Wenming Li,Jarron Roy,Yan Bao*,Jianjun Cheng*,Targeting infected host cells in vivo via responsive azido-sugar mediated metabolic cell labeling followed by click reaction,Biomaterials,2020 April; 238:119843.(影响因子12.9,中科院SCI期刊大类分区:医学1区) ISSN: 0142-9612,Cuiyu Zhong#,Jie Li#,Suiping Liu,Weirong Li,Qiang Zhang,Junpeng Zhao,Menghua Xiong*,Yan Bao*,Yandan Yao*,Nanoblock-mediated selective oncolytic polypeptide therapy for triple-negative breast cancer,Theranostics,2023; 13(9): 2800-2810. doi: 10.7150/thno.81834.(影响因子13.3,中科院SCI期刊大类分区:医学1区)ISSN: 1838-7640,Weinan Zhang#,Xiaochuan Wang#,Jihong Wang#,Chanjuan Su,Yan Bao*,Menghua Xiong*,The relationship between in vivo toxicity and responsive pH in transistor-Like pH-sensitive nanodetergents,Small Methods,2025 May;9(5):e2401263. (影响因子9.1,中科院SCI期刊大类分区:材料科学2区)ISSN:2366-9608,Yuhao Zhang,Yingxue Deng1,Chanjuan Su,Kangxiu Wu,Chengrun Li,Juntao Wang,Houbing Zhang,Dong Luo,Songyin Huang,Liping Zhao,Megnhua Xiong*,Yan Bao*,A conjugate strategy capable of targeting bacteria and selectively being activated at infection sites,Science China Materials,2025 may 68(6):2132-2142(影响因子7.4,中科院SCI期刊大类分区:材料科学1区) ISSN: 2095-8226,Yan Bao#,Xuewei Wu#,Jinjing Chen,Xiangming Hu,Fuxing Zeng,Jianjun Cheng,Hong Jin,Xin Lin,Lin-Feng Chen*,Brd4 modulates the innate immune response through Mnk2-eIF4E pathway-dependent translational control of IκBα,Proceedings of the National Academy of Sciences of the United States of America,2017 May 16;114(20):E3993-E4001.(影响因子9.1,中科院SCI期刊大类分区:综合性期刊1区)ISSN: 0027-8424被Faculty 1000推荐为2星论文,Menghua Xiong#,Yan Bao#,Xin Xu#,Hua Wang,Zhiyuan Han,Zhiyu Wang,Yeqing Liu,Songyin Huang,Ziyuan Song,Jinjing Chen,Richard M. Peek Jr.,Lichen Yin*,Lin-Feng Chen*,Jianjun Cheng*,Selective killing of Helicobacter pylori with pH-responsive helix-coil conformation transitionable antimicrobial polypeptides,Proceedings of the National Academy of Sciences of the United States of America,2017 Nov 28;114(48):12675-12680.(影响因子9.1,中科院SCI期刊大类分区:综合性期刊1区)ISSN: 0027-8424