张寅，副研究员，硕士生导师。从事RNA蛋白相互作用、基因组和表观调控在肿瘤中功能和机制研究。到目前为止以第一或者通讯作者的身份发表SCI收录论文16篇。包括Nucleic Acids Research、Cancer Research、Autophagy、Theranostics、Journal of Nanobiotechnology等等高水平专业杂志。本人研究受到了3项国家和省部级基金资助。目前本人兴趣点主要在利用生物信息和人工智在表观组、基因组和转录组层面发掘肿瘤调控的新机制，同时我们还开发建立了一系列原创的方法和工具，从新的角度揭示肿瘤的发生发展和耐药的深层分子机制和临床意义。联系方式：zhangy525@mail.sysu.edu.cn，代表性文章：1. Yun Li#，Hengxing Chen#，Xuan Xie#，Bing Yang，Xiaojuan Wang，Jingyuan Zhang，Tian Qiao，Jiao Guan，Yuntan Qiu，Yong-Xin Huang，Duanqing Tian，Xinyi Yao，Daning Lu，H Phillip Koeffler，Yin Zhang*(共同通讯)，Dong Yin*，PINK1-Mediated Mitophagy Promotes Oxidative Phosphorylation and Redox Homeostasis to Induce Drug-Tolerant Persister Cancer Cells，Cancer Research，2023 Feb 3;83(3):398-413，2. Ying Liu#，Guangwei Ma#，Zenghong Gao，Jian Li，Jin Wang，Xiangping Zhu，Ruowu Ma，Jiawen Yang，Yiting Zhou，Kaishun Hu，Yin Zhang*(共同通讯)，Yabin Guo*，Global chromosome rearrangement induced by CRISPR-Cas9 reshapes the genome and transcriptome of human cells，Nucleic Acids Research，2022;50(6):3456-3474，3. Yun Li#，Hengxing Chen#，Daning Lu，H Phillip Koeffler，Yin Zhang*(共同通讯)，Dong Yin*，Mitophagy is a novel protective mechanism for drug-tolerant persister (DTP) cancer cells，Autophagy，2023 Feb 15;1-2，3. Yin Zhang#（第一作者），Yong-xin Huang#，Dan-lan Wang，Bing Yang，Hai-yan Yan，Le-hang Lin，Yun Li，Jie Chen，Li-min Xie，Yong-sheng Huang，Jian-you Liao，Kai-shun Hu，Jie-hua He，Phei Er Saw，Xiao-ding Xu，Dong Yin*，LncRNA DSCAM-AS1 interacts with YBX1 to promote cancer progression by forming a positive feedback loop that activates FOXA1 transcription network，Theranostics，2020; 10(23): 10823-10837，4. Yin Zhang#（第一作者），Yong-Xin Huang#，Xin Jin#，Jie Chen，Li Peng，Dan-Lan Wang，Yun Li，Xin-Yi Yao，Jian-You Liao，Jie-Hua He，KaiShun Hu，Daning Lu，Yabin Guo*，Dong Yin*，Overexpression of lncRNAs with endogenous lengths and functions using a lncRNA delivery system based on transposon，Journal of Nanobiotechnology，2021 Oct，19(1):303，6. Yin Zhang#（第一作者），Ye-Ya Tan #，Pei-Pei Chen #，Hui Xu，Shu-Juan Xie，Shi-Jun Xu，Bin Li，Jun-Hao Li，Shun Liu，Jian-Hua Yang，Hui Zhou，Liang-Hu Qu*. Genome-wide identification of microRNA targets reveals positive regulation of the Hippo pathway by miR-122 during liver development，Cell Death and Disease，2021 Dec 14; 12(12):1161，7. Zixian Huang#，Yin Zhang#（共同一作），Haigang Li，Yufeng Zhou，Qianyu Zhang，Rui Chen，Tingting Jin，Kaishun Hu，Shihao Li，Yan Wang，Weiliang Chen*，Zhiquan Huang*，Vitamin D promotes the cisplatin sensitivity of oral squamous cell carcinoma by inhibiting LCN2-modulated NF-κB pathway activation through RPS3，Cell Death and Disease，2019 Dec 9;10(12):936，8. Ye-Ya Tan#，Yin Zhang#（共同一作），Bin Li，Yang-Wen Ou，Shu-Juan Xie，Pei-Pei Chen，Shi-Qiang Mei，Qiao-Juan Huang，Ling-Ling Zheng，Liang-Hu Qu*，PERK Signaling Controls Myoblast Differentiation by Regulating MicroRNA Networks，Frontiers in Cell and Developmental Biology，2021 May 28;9:670435，9. Qianyu Zhang#，Zixian Huang#，Xi Rui#，Yan Wang#，Yongqiang Wang，Yuwei Zhou，Rui Chen，Yongju Chen，Yuepeng Wang，Shihao Li，Haigang Li，Ximing Shen，Yancan Liang，Yin Zhang*(共同通讯)，Zhiquan Huang*，GSDMD enhances cisplatin-induced apoptosis by promoting the phosphorylation of eIF2α and activating the ER-stress response，Cell Death Discovery，(2022) 8:114