刘文佳，博士，西安交通大学第二附属医院生物诊疗中心特聘教授，博士生导师，西安交通大学“青年拔尖人才”A类人才，英国卡迪夫大学及首尔大学访问学者。参与获得陕西省科技进步一等奖2项，获得陕西省优秀博士论文。担任中国生物医学工程学会组织工程与再生医学分会常务委员、中华口腔医学会口腔生物医学专业委员会委员。担任西安组织工程与再生医学研究所副所长。主持国家自然科学基金面上项目2项、青年项目1项。承担国家重点研发计划子课题2项，是教育部“创新团队”核心成员，国家自然科学基金重点项目及国际合作与交流项目学术骨干。主要从事干细胞功能调控与重大疾病治疗及康复研究。近年来发表SCI论文25篇，其中以第一作者和通讯作者发表SCI论文20篇，累计影响因子125。其中影响因子10分以上1篇，5分以上15篇，论文在Bone Research、Theranostics、Aging Cell、Aging等杂志发表。相关研究获2018年第七届口腔生物医学优秀青年研究一等奖、2017年第一届中国组织工程与再生医学优秀青年研究奖，2012年IADR青年学者研究奖。获实用新型专利2项、外观专利2项、申请发明专利5项。受邀参编“十二五”规划研究生教材等3部书籍。代表性论文：1. Zhang Zhang#，Shuai Yi#，Zhou Feng，Yin Jikai，Hu Jiachen，Guo Songling，Wang Yan，Liu Wenjia*.PDLSCs Regulate Angiogenesis of Periodontal Ligaments via VEGF Transferred by Exosomes in Periodontitis.Int J Med Sci. 2020 Feb 10;17(5):558-567.，2. Zhang Zhang#，Zhang Liqiang#，Zhou You，Li Liya，Zhao Jiangdong，Qin Wen，Jin Zuolin，Liu Wenjia*.Increase in HDAC9 suppresses myoblast differentiation via epigenetic regulation of autophagy in hypoxia. Cell Death Dis. 2019 Jul 18;10(8):552.，3. Liu Wenjia#，Zhang Liqiang#，Xuan Kun，Hu Chenghu，Liu Shiyu，Liao Li，Li Bei，Jin Fang，Shi Songtao，Jin Yan*.Alplprevents bone ageing sensitivity by specifically regulating senescence and differentiation in mesenchymal stem cells. Bone Res. 2018; 6: 27.，4. Zhang Zhang#，Liqiang Zhang#，You Zhou#，Liya Li，Jiangdong Zhao，Wen Qin，Zuolin Jin*，Wenjia Liu*.Increase of HDAC9 restrains myoblast differentiation via epigenetically regulation of autophagy in hypoxia. Cell Death Dis. 2019，5. Liu Wenjia#，Zhang Liqiang#，Xuan Kun#，Hu Chenghu，Li Liya，Zhang Yongjie，Jin Fang*，Jin Yan*. Alkaline Phosphatase Controls Lineage Switching of Mesenchymal Stem Cells by Regulating the LRP6/GSK3β Complex in Hypophosphatasia. Theranostics. 2018; 8(20): 5575-5592.，6. Li Liya#，Liu Wenjia#，Wang Hong，Yang Q，Zhang L，Jin F*，Jin Y*. Mutual inhibition between HDAC9 and miR-17 regulates osteogenesis of human periodontal ligament stem cells in inflammatory conditions. Cell Death Dis. 2018; 9(5): 480.，7. Shuai Yi#，Ma Yang#，Guo Tao#，Zhang Liqiang，Yang Rui，Qi Meng，Liu Wenjia*，Jin Yan*. Dental Stem Cells and Tooth Regeneration. Adv Exp Med Biol. 2018; 1107: 41-52.，8. Ma Yang#，Qi Meng#，An Ying，Zhang Liqiang，Yang Rui，Doro H Daniel，Liu Wenjia*，Jin Yan*. Autophagy controls mesenchymal stem cell properties and senescence during bone aging. Aging Cell. Aging Cell. 2018; 17(1).，9. Qi Meng#，Zhang Liqiang#，Ma Yang#，Shuai Yt，Li Liya，Luo Kefu，Liu Wenjia*，Jin Yan*. Autophagy Maintains the Function of Bone Marrow Mesenchymal Stem Cells to Prevent Estrogen Deficiency-Induced Osteoporosis. Theranostics. 2017; 7(18): 4498-4516.，10. An Ying#，Liu Wenjia#，Xue Peng，Ma Yang，Zhang Liqiang，Zhu Bin，Qi Meng，Li Liya，Zhang Yongjie，Wang Qingtao*，Jin Yan*. Autophagy promotes MSC-mediated vascularization in cutaneous wound healing via regulation of VEGF secretion. Cell Death Dis. 2018; 9(2): 58.，11. Zhu Bin#，Liu Wenjia#，Liu Yihan，Zhao Xicong，Zhang Hao，Luo Zhuojing*，Jin Yan*. Jawbone microenvironment promotes periodontium regeneration by regulating the function of periodontal ligament stem cells. Sci Rep. 2017; 7: 40088.，12. Zhang Liqiang#，Liu Wenjia#，Zhao Jiangdong，Ma Xiaojie，Shen Linlin，Zhang Yongjie，Jin Fang*，Jin Yan*. Mechanical stress regulates osteogenic differentiation and RANKL/OPG ratio in periodontal ligament stem cells by the Wnt/β-catenin pathway. Biochim Biophys Acta. 2016; 860(10): 2211-2219.，13. An Ying#，Liu Wenjia#，Xue Peng，Zhang Yongjie，Wang Qintao*，Jin Yan*. Increased autophagy is required to protect periodontal ligament stem cells from apoptosis in inflammatory microenvironment. J Clin Periodontol. 2016; 43(7): 618-625.，14. Liu Wenjia#，Qi Meng#，Konermann Anna#，Zhang Liqiang，Jin Fang*，Jin Yan*. The p53/miR-17/Smurf1 pathway mediates skeletal deformitiesin an age-related model via inhibiting the function of mesenchymal stem cells. Aging-US. 2015; 7(3): 205-218.，15. Guo Tao#，Zhang Liqiang#，Konermann Anna，Zhou Hong，Jin Fang*，Liu Wenjia*. Manganese superoxide dismutase isrequired to maintain osteoclastdifferentiation and function under staticforce. Sci Rep.2015; 5: 8016.，16. Zhu Bin#，Liu Wenjia#，Zhang Hao#，Zhao Xicong，Duan Yan，Li Dehua*，Jin Yan*. Tissue-specific composite cell aggregates drive periodontium tissue regeneration by reconstructing a regenerative microenvironment. J Tissue Eng Regen Med. 2017; 11(6): 1792-1805.，17. Liu Jia#，Wang Liying#，Liu Wenjia#，Li Qiang，Jin Zuolin*，Jin Yan*. Dental follicle cells rescue the regenerative capacity of periodontal ligament stem cells in an inflammatory microenvironment. PLoS One. 2014; 9(9): e108752.，18. Liu Wenjia#，Liu Yali#，Guo Tao，Hu Chenghu，Luo Hailang，Zhang Liqiang，Shi Songtao，Cai Tao，Ding Yin*，Jin Yan*. TCF3，a novel positive regulator of osteogenesis，plays a crucial role in miR-17 modulating the diverse effect of canonical Wnt signaling in different microenvironments. Cell Death Dis. 2013; 4: e539.，19. Liu Wenjia#，Konermann Anna#，Guo Tao#，Jäger Andreas，Zhang Liqiang，Jin Yan*. Canonical Wnt signaling differently modulates osteogenic differentiation of mesenchymal stem cells derived from bone marrow and from periodontal ligament under inflammatory conditions. Biochim Biophys Acta. 2013; 1840(3): 1125-1134.，20. Liu Yali#，Liu Wenjia#，Hu Chenghu，Xue Zengfu，Wang Guang，Ding Bofu，Luo Hailang，Tang Liang，Kong Xiangwei，Chen Xiaoyan，Liu Na，Ding Yin*，Jin Yan*. MiR-17 modulates osteogenic differentiation through a coherent feed-forward loop in mesenchymal stem cells isolated from periodontal ligaments of patients with periodontitis.Stem Cells. 2011; 29(11): 1804-1816.