自1993年7月硕士研究生毕业后，一直在暨南大学附属第一医院呼吸与危重症医学科（呼吸内科）从事临床、教学及科研工作，具有丰富的理论知识和临床经验；同时承担暨南大学博士及硕士研究生、本科生的教学工作。1998-1999年赴德国留学进修呼吸病学。2002年－2005年在广州医科大学广州呼吸疾病研究所攻读呼吸内科学博士学位。【学术任职】中华医学会呼吸病学分会委员，广东省医学会呼吸分会主任委员兼慢阻肺学组组长，中国医师协会呼吸医师分会慢阻肺工作委员会委员，中国医药教育协会呼吸病康复专业委员会常委，广东省呼吸内科专业质量控制中心副主任，广东省医师协会内科医师分会副主任委员，广东省呼吸与健康学会副会长，广东省药学会呼吸用药专家委员会副主任委员，广东省健康管理学会呼吸专业委员会副主任委员，广东省医学会结核病学分会常委，广州市医师协会呼吸医师分会副主任委员，广东省临床医学学会感染性疾病精准诊疗专业委员副主任委员，广东省医学会和广州市医学会医疗技术鉴定专家库成员等。【主研方向】主要研究方向为慢性阻塞性肺疾病及肺癌的诊断和治疗。承担和参加国家级、省部级及厅局级课题十余项。【获奖情况】《慢性阻塞性肺疾病发病与人群防治研究》荣获2013年广东省科学技术奖励一等奖，《γ-谷氨酰半胱氨酸合成酶在COPD发病中的作用与机制研究》荣获2012年广东省科学技术奖励二等奖；荣获广东省优秀博士学位论文，2003年抗击传染性非典型肺炎工作中荣获广东省个人三等功及广州市抗击非典先进个人称号，2023年荣获广东省医疗系统先进个人，曾荣获暨南大学优秀共产党员、暨南大学先进医务工作者、暨南大学管理服务先进个人、暨南大学第一临床医学院教学工作暨本科教学评估先进个人二等奖等荣誉。【学术论著】已在SCI、核心期刊及统计源期刊上发表呼吸专业学术论文100余篇，其中发表SCI论文50余篇，有2篇为高频被引SCI论文。2020年至今发表论文（仅通讯作者）：1. Yihui Fu，Yamei Zheng，Liang Li，Zhao Li，Jiwei Li，Shengming Liu. FTO-Mediated Downregulation of RAMP2-AS1 Promotes Glycolysis in Non-Small Cell Lung Cancer Cells by Inhibiting KLF9-Mediated Transcriptional Activation of LATS2. J BIOL REG HOMEOS AG，2024?38(5):4223-4237.，2. Wen Dong，Rong Xie，Nan Yang，Shengming Liu. Zn(II) Coordination Polymer: Luminescence Sensing for Fe3+ Ion and Used as Metal Gel Particles Against Lung Cancer. J FLUORESC，2023-12-29. DOI:10.1007/s10895-023-03547-y.，3. Shuai Yang，Yuxin Zhang，Yan He，Shengming Liu. Comparison of Prognostic Scores for Patients with COVID-19 Presenting with Dyspnea in the Emergency Department. J Emerg Med，2023;65(6):e487-e494.，4. Zewei Jiang，Jiaxin Wang，Xingdong Cai，Ping Wang，Shengming Liu. L-shaped association of serumα-Klotho and frailty among the middle-aged and older adults: results from NHANES 2007-2016. BMC Geriatrics，2023，23(1):716.，5. Li Che，Zhefan Xie，Guangshu Chen，Wei Zhang，Tingting Xia，Jiaxin Lin，Wenzhi Luo，Li Chen，Wenguang Yin，Xingdong Cai，Shengming Liu. The Mechanisms of Resistin-Like Molecule-β-Mediated Airway Inflammation in Chronic Obstructive Pulmonary Disease via Autophagy. J INFLAMM RES. 2023，16:3853-3870.，6. Tao Wang，Peng Fu，Fa Long，Shengming Liu，Siyu Hu，Qiongping Wang，Zhihui Huang，Liang Long，Wenting Huang，Fengbo Hu，Jingfan Gan，Hongbo Dong and Guomei Yan. Research on the effectiveness and safety of bronchial thermoplasty in patients with chronic obstructive pulmonary disease. EUR J MED RES. 2023，28(1):331.，7. Xinyi Cao，Yongzhi Liang，Honglin Feng，Li Chen，Shengming Liu. Construction and evaluation of a risk prediction model for pulmonary infection-associated acute kidney injury in intensive care units. Clin Transl Sci，2023;16(10):1923-1934.，8. Shuaishuai Wu，Changli Wang，Ning Li，Augustine K Ballah，Jun Lyu，Shengming Liu，Xiangyu Wang. Analysis of Prognostic Factors and Surgical Management of Elderly Patients with Low-Grade Gliomas. World Neurosurg，2023，E20-E31.，9. Ning Li，Yuanxiong Cheng，Shiyong Wang，Hua Liao，Shengming Liu. Inhibition of airway smooth muscle contraction and proliferation by LIM kinase inhibitor，LIMKi3. Advances in Medical Sciences，2023，68(2):186-194.，10. Xu Chen，Yonglan Yang，Gang Ye，Shengming Liu，Jie Liu. Chiral Ruthenium Nanozymes with Self-Cascade Reaction Driven the NO Generation Induced Macrophage M1 Polarization Realizing the Lung Cancer“Cocktail Therapy”. Small，2023，19(28):2207823.，11. Jing Yang，Ge Shan，Guangchao Yu，Jie Wei，Qinghuan Zhang，Wen Su，Qiuping Lin，Zhixiong Zheng，Guangliang Wu，Guangtian Li，Qing Chang，Hong Yuan，Yanju He，Yanling Chen，Yi Zhang，Haile Huang，Wan Hu，Rongqing Song，Yuqing Weng，Xiaobin Li，Shengming Liu. Whole genome sequencing of multidrug-resistant Proteus mirabilis strain PM1162 recovered from a urinary tract infection in China. J GLOB ANTIMICROB RE.2023，33:44-50.，12. Zhefan Xie，Tingting Xia，Xingdong Cai，Li Che，Shengming Liu. Identification of the key genes in chronic obstructive pulmonary disease by weighted gene co-expression network analysis. Ann Transl Med. 2022;10(12):665. doi:10.21037/atm-22-2523.，13. Li Che，Guangshu Chen，Xingdong Cai，Zhefan Xie，Tingting Xia，Wei Zhang，Shengming Liu. Bioinformatics Approach Predicts Candidate Targets for SARS-CoV-2 Infections to COPD Patients. BIOMED RES INT. 2022，1806427.，14. Wei Zhang，Qian Zhang，Zhefan Xie，Li Che，Tingting Xia，Xingdong Cai，Shengming Liu. N6-Methyladenosine-Related Long Non-Coding RNAs Are Identified as a Potential Prognostic Biomarker for Lung Squamous Cell Carcinoma and Validated by Real-Time PCR. Front Genet，2022，13:839957.，15. Yuanyuan Liu，Shuyu Chen，Li Yua，Yao Deng，Difei Li，Xiu Yu，Dandan Chen，Ye Lu，Shengming Liu，Rongchang Chen. Pemafibrate attenuates pulmonary fibrosis by inhibiting myofibroblast differentiation. INT IMMUNOPHARMACOL，2022;108:108728.，16.Wei Zhang，Qian Zhang，Li Che，Zhefan Xie，Xingdong Cai，Ling Gong，Zhu Li，Daishun Liu and Shengming Liu. Using biological information to analyze potential miRNA-mRNA regulatory networks in the plasma of patients with non-small cell lung cancer. BMC Cancer.2022;22(1):299.，17. Xiaoyu Zhou，Haitao Liu，Yingying Pang，Muqun Wang，Shengming Liu. UTMD-mediated delivery of miR-21-5p inhibitor suppresses the development of lung cancer. TISSUE CELL，2022，101719.，18. Shuyu Chen，Zhuoyu Chen，Yao Deng，Zha Shanshan，Li Yu，Difei Li，Zhenyu Liang，Kai Yang，Shengming Liu，Rongchang Chen. Prevention of IL-6 signaling ameliorates toluene diisocyanate-induced steroid-resistant asthma. ALLERGOL INT，2022;71(1):73-82.，19. Li Che，Chao Yu，Guangshu Chen，Jiaxin Lin，Zhefan Xie，Tingting Xia，Wenzhi Luo，Xingdong Cai，Shengming Liu. The Inflammatory Response Induced by RELM beta Upregulates IL-8 and IL-1 beta Expression in Bronchial Epithelial Cells in COPD. INT J CHRONIC OBSTR，2021;16:2503–2513.，20. Zhaohui Liu，Zheng Hu，Xingdong Cai，Shengming Liu. SLC39A5 promotes lung adenocarcinoma cell proliferation by activating PI3K/AKT signaling. PATHOL RES PRACT，2021，224:153541.，21.Kai Yang，Ying Wu，Dandan Chen，Shengming Liu，Rongchang Chen. The Impact of Lung Function on Extra-Pulmonary Diseases and All-Cause Mortality in US Adult Population with and without COPD. Clin Epidemiol，2020;12:997–1005.，22. Li Chen，Liqiong Yu，Yi Wu，Wai-kit Ming，Zhihong Huang，Shengming Liu. A 52-Year-Old Man With an 11-Month History of Fever，Cough，Chest Pain，Pleural Effusion，and Left Lung Atelectasis. Chest，2020，158(4):e153-e157.，23. Peng Zhang，Yan Chen，Shuyun Li，Chaoliang Li，Shuang Zhang，Weihao Zheng，Yantang Chen，Jie Ma，Xin Zhang，Yanming Huang，Shengming Liu. Metagenomic next-generation sequencing for the clinical diagnosis and prognosis of acute respiratory distress syndrome caused by severe pneumonia: a retrospective study. PeerJ，2020;8:e9623. DOI 10.7717/peerj.9623.